Local authorities in Edgewood, New Mexico, summon the BAU to investigate a truck driver who is kidnapping women and disposing of them in random locations as he apparently tries to find a new mother for his daughter.

The BAU is called by local authorities in Ashburn, Virginia, to profile a predator who may have been abducting children for at least eight years.

The BAU is summoned to Rhode Island to investigate a serial killer in Providence who is murdering random victims in highly visible places just to generate public fear.

The BAU is called by local authorities in Miami to profile a con artist who has begun to eliminate the people involved in his criminal schemes.

The BAU is called to assist local authorities in rural Wyoming when teens are found dead from apparent suicide that are linked to a game on the internet.

The BAU is called to Atlantic City to profile a suspect with an unusual personal obsession who is abducting and killing certain a certain type of woman.

After an ex-convict makes a daring escape from the BAU's custody and embarks on a violent killing spree in Lockport, New York, the team must profile the criminal's past career in order to stop him.

While Agent Hotchner takes a leave of absence to contemplate his future with the BAU, the team is called to investigate a home invasion case in Nashville without him.

When The Reaper returns to Washington for a final showdown, the team works frantically to catch him before he reaches SSA Hotchner's family.

While investigating a series of murders of entire families in Hampton, Virginia, the BAU is forced to visit Red Onion State Prison to seek advice from one of the most atrocious killers from the team's past, nicknamed "The Fox," who delivers a portentous message to Agent Hotchner.

The BAU is called to Los Angeles to investigate a series of killings that lead to a Goth rock star who appears to have become lost in the creepy alter-ego he portrays when he is on stage.

The BAU is called to Oklahoma City to help local authorities track a serial killer who removes the eyes of his murder victims and keeps the eyes as souvenirs.

The BAU travels to Albuquerque to investigate the case of a serial killer who impregnates young women and murders them after they have given birth.

The BAU investigates a group of suspects with a pack mentality who are randomly selecting their victims in the nation's capital and murdering them for the thrill of it.

SSA David Rossi's personal and professional life is brought to the forefront when the BAU is called to investigate a case in Commack, Long Island, Agent Rossi's hometown.

The BAU is called to Louisville to help local authorities determine what caused a disturbed man to murder several people at a pharmacy before he harms anyone else.

As Rossi, Morgan and JJ profile a killer who is targeting an emergency room doctor, Prentiss realizes that Hotch is missing.